Predictors of no-reflow in patients with myocardial infarction and ST-segment elevation treated with primary angioplasty

Abstract Introduction The no-reflow phenomenon is a serious complication of coronary intervention, especially in primary angioplasty and effective preventive measures are unknown. Methods Retrospective study all patients treated by single center through 4 years. We define as the absence flow immediately after stent angioplasty. variables associated with this were analyzed using binary logistic regression. delay to was calculated sum time first medical contact, activation, transfer until arterial puncture. Results included 1453 patients, mean age 64.1 years, 21% women, 16.1% Killip >1. 180 minutes (interquartile range 125–323). No-reflow recorded 81 (5.57%) these had higher (69.37±12.51 vs. 63.76±13.52; p<0.001), (770.93±2056.91 348.80±749.73; presentation grade >1 (29.0% 15.36%; p=0.002), addition lower systolic blood pressure (121.18±28.63 113.37±28.22; p=0.021). Regarding angiography, who developed presented more frequently TIMI-0 (88.89% 70.32%; p<0.001) tendency being left anterior descending culprit vessel (46.91% 36.88, p=0.07). In 59.3% no-reflow, final TIMI 3 achieved, measurements carried out, compared (94.9%) did not have (p<0.001). Multivariate analysis identified following no-reflow: (OR: 1.03 95% CI 1.01–1.05; p=0.008), >120 min 2.70, 1.21–6.00; p=0.015), initial 3.22, 1.57–6.58; p=0.001). fact, aged >40 very low incidence (1.72%), regardless angioplasty; however, >70 years age, much (figure) Hospital mortality 9.25% (125 patients) almost times (23.68% 8.39%; p<0.001). Adjusted for sex, diabetes flow, hospital 2.34 1.02 4.25; p=0.030) Conclusions has but high ST-segment elevation myocardial infarction Age, 0 main predictors no-reflow. Funding Acknowledgement Type funding sources: None.